Active Recombinant Human KDR Protein, Fc-tagged, FITC conjugated

KDR has a lower affinity for VEGF than theFlt-1 receptor, but a higher signaling activity. Mitogenic activity inendothelial cells is mainly mediated by KDR leading to their proliferation.Differential splicing of the flt-1 gene leads to the formation of a secreted,soluble variant of VEGFR-1 (sVEGFR-1). No naturally occurring, secreted formsof KDR have so far been reported. The binding of VEGF165 to KDR is dependenton heparin.

• Supplier: Creative Biomart
• Product #: KDR-5442HF
• Product Category: Recombinant Protein
• Shipping Country: USA