Human Anti-SIGLEC7 Recombinant Antibody (clone AK446-7/AK448-3)
Provided herein are antibodies that specifically bind to Siglec-7. The antibodies demonstrated KD values (monovalent Fab) of about 75 nM or lower. The results showed that anti-Siglec-7 antibodies blocked the interaction of Siglec-7 with ligands present on the surface of A375 melanoma human cells with various potencies and demonstrated antibodies that have improved ligand blocking activity.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-N0244-YC |
| Pricing | Inquiry |
| Host | Human |
| Target | SIGLEC7 |
| Species Reactivity | Human |
| Type | Humanized IgG |
| Applications | Block |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |