Talacotuzumab ELISA Kit
Talacotuzumab ELISA Kit is a quantitative ELISA kit for detection of Talacotuzumab.
Talacotuzumab (TAL, JNJ-56022473) is an IgG1 monoclonal antibody targeting CD123 preferentially via antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells and has been shown to induce potent in vitro ADCC against IL3RA-expressing AML blasts/LSC and to reduce leukemic cell growth in murine xenograft models of human AML. In addition, the antibody inhibits signaling by IL-3, the main ligand of CD123, to reduce the proliferation of leukemic progenitor cells.
Talacotuzumab (TAL, JNJ-56022473) is an IgG1 monoclonal antibody targeting CD123 preferentially via antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells and has been shown to induce potent in vitro ADCC against IL3RA-expressing AML blasts/LSC and to reduce leukemic cell growth in murine xenograft models of human AML. In addition, the antibody inhibits signaling by IL-3, the main ligand of CD123, to reduce the proliferation of leukemic progenitor cells.
Supplier | Abbexa Ltd. |
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Product # | abx395103-96T |
Pricing | 96 tests USD $942.5 |
Tested Applications | ELISA |
Test Range | 0.31 μg/ml - 5 μg/ml |
CAS Number | 1826831-79-1 |
Availability | Shipped within 5-12 working days. |
Dry Ice | No |
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