Temozolomide Acid
Temozolomide acid is an active metabolite of temozolomide(T017775) with anticancer activity in vitro. Temozolomide is an alkylating agent used as a treatment of some brain cancer, a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.In Apr 2016, Stanford University and Merck suspended enrolment in a phase II trial for Acute myeloid leukaemia (Combination therapy, Newly diagnosed, Second-line therapy or greater) in USA. In 14 Jul 2016, Medivation planed a phase II trial for Endometrial cancer in USA (NCT02836028) After two days, M.D. Anderson Cancer Center completed a phase II trial in Malignant melanoma (Late-stage disease, Neoadjuvant therapy, Monotherapy, Combination therapy) in USA .
| Supplier | BOC Sciences |
|---|---|
| Product # | B2694-161090 |
| Pricing | Inquire |
| Cas | 113942-30-6 |
| Molecular Weight | 195.14 |
| Molecular Formula | C6H5N5O3 |
| Canonical SMILES | CN1C(=O)N2C=NC(=C2N=N1)C(=O)O |