Samidorphan
Samidorphan, also known as ALKS-33 and RDC-0313, is an opioid modulator with μ-antagonist properties. It is under development by Alkermes for the treatment of major depressive disorder and possibly other psychiatric conditions.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1136 |
| CAS # | 852626-89-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | Samidorphan; RDC 0313; RDC-0313; RDC0313; ALKS-33; ALKS33; ALKS 33; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H26N2O4 |
| Exact Mass | 370.1893 |
| Molecular Weight | 370.44 |
| Elemental Analysis | C, 68.09; H, 7.07; N, 7.56; O, 17.28 |
| IUPAC/Chemical Name | (4bR,8aS,9R)-11-(cyclopropylmethyl)-4,8a-dihydroxy-6-oxo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-3-carboxamide |
| InChi Key | RYIDHLJADOKWFM-MAODMQOUSA-N |
| InChi Code | InChI=1S/C21H26N2O4/c22-19(26)15-4-3-13-9-16-21(27)6-5-14(24)10-20(21,17(13)18(15)25)7-8-23(16)11-12-1-2-12/h3-4,12,16,25,27H,1-2,5-11H2,(H2,22,26)/t16-,20-,21-/m1/s1 |
| SMILES Code | O=C(C(C(O)=C1[C@@]23C4)=CC=C1C[C@@H](N(CC5CC5)CC3)[C@]2(O)CCC4=O)N |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.03.00 |