Sorafenib Tosylate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10201A-10 mM * 1 mL |
| CAS # | 475207-59-1 |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Synonyms | Bay 43-9006 Tosylate |
| MWt | 637.03 |
| Formula | C₂₈H₂₄ClF₃N₄O₆S |
| Biological Activity | Sorafenib Tosylate (Bay 43-9006 Tosylate) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. SorafenibTosylate is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib Tosylate induces autophagy and apoptosis. Sorafenib Tosylate has anti-tumor activity. Sorafenib Tosylate is a ferroptosis activator[1]. |
| Purity | ≥98.0% |