Ferulic Acid
Ferulic Acid is a fibroblast growth factor receptor 1 (FGFR1) inhibitor that has antioxidant, anti-inflammatory and anticancer properties. Ferulic acid increased monoamine neurotransmitter levels in the brain regions that are relative to mood disorders: the hippocampus and frontal cortex. The increased tend to serotonin and norepinephrine was also found in the hypothalamus after higher dose of ferulic acid treatment. Monoamine oxidase A (MAO-A) activity was inhibited in the frontal cortex and hippocampus when treatment with 40 and 80 mg/kg ferulic acid; while MAO-B activity did not change significantly. Ferulic acid provides neuroprotective effects against a middle cerebral artery occlusion (MCAO)-induced cerebral ischemia.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD851 |
| CAS # | 1135-24-6 |
| Pricing | Customizable size, Inquiry |
| Synonym | Ferulic Acid, Methyl ferulate, trans-Ferulic acid, Coniferic acid, NSC 2821, NSC2821, NSC-2821 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C10H10O4 |
| Exact Mass | 194.0579 |
| Molecular Weight | 194.186 |
| Elemental Analysis | C, 61.85; H, 5.19; O, 32.96 |
| IUPAC/Chemical Name | (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid |
| InChi Key | KSEBMYQBYZTDHS-HWKANZROSA-N |
| InChi Code | InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ |
| SMILES Code | O=C(O)/C=C/C1=CC=C(O)C(OC)=C1 |
| Appearance | White to light yellow crystalline powder. |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |