Perphenazine
Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. Perphenazine blocks postsynaptic dopamine 2(D2) receptors in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby preventing the excess of dopamine in the brain. This leads to reduction in psychotic symptoms, such as hallucinations and delusions.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1648 |
| CAS # | 58-39-9 |
| Pricing | Customizable size, Inquiry |
| Synonym | Perphenazine; Trilafon; Perphenazin; Perfenazine; Etaperazine; Chlorpiprazine |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H26ClN3OS |
| Exact Mass | 403.1485 |
| Molecular Weight | 403.969 |
| Elemental Analysis | C, 62.44; H, 6.49; Cl, 8.78; N, 10.40; O, 3.96; S, 7.94 |
| IUPAC/Chemical Name | 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol |
| InChi Key | RGCVKNLCSQQDEP-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 |
| SMILES Code | C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO |
| Appearance | White to off-white crystalline powder. |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |