Mouse Anti-TFPI Recombinant Antibody (clone 2F22)
This product is a recombinant Mouse antibody that can recognize TFPI. mAb2F22, was raised against the N-terminal fragment of TFPI (1-79). mAb2F22 bound exclusively to the K1 domain of TFPI (KD ∼1 nm) and not to the K2 domain. mAb2F22 interfered with inhibition of both FVIIa and FXa activities and restored clot formation. mAb2F22 blocked TFPI inhibition of both FVIIa and FXa activities and mapped a FXa exosite for binding to K1.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABC-461 |
| Pricing | Inquiry |
| Host | Mouse |
| Target | TFPI |
| Species Reactivity | Human |
| Type | Mouse IgG1, κ |
| Applications | FuncS, ELISA, FC, Neut |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |