NLRP3-IN-NBC6
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-131040 |
| CAS # | 2068818-02-8 |
| Pricing | inquire |
| Biological Activity | NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor (IC50= 574 nM) that acts independently of Ca2+. NLRP3-IN-NBC6 inhibits Nigericin (HY-127019)-induced inflammasome activation in THP-1 cells and Imiquimod (HY-B0180)-induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs)[1]. |
| MWt | 409.5 |
| Formula | C₁₈H₁₆BCl₃N₂O₂ |