Cyclotraxin B
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-P1178 |
| CAS # | 1203586-72-4 |
| Pricing | inquire |
| Biological Activity | Cyclotraxin B, a cyclic peptide, is a highly potent and selective TrkB inhibitor without altering the binding of BDNF. Cyclotraxin B non-competitively inhibits BDNF-induced TrkB activity with an IC50 of 0.30 nM. Cyclotraxin B can crosse the blood-brain-barrier and has analgesic and anxiolytic-like behavioral effects[1][2][3]. |
| MWt | 1200.37 |
| Formula | C₄₈H₇₃N₁₃O₁₇S₃ |