Pipequaline HCl
Pipequaline, also known as PK-8165, is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic. Pipequaline acts as a non-selective GABAA receptor partial agonist. While its profile of anxiolytic effects without sedation would appear to have potential medical applications, pipequaline has never been developed for medical use and is currently only used in scientific research.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD355 |
| CAS # | 80221-58-5 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Pipequaline; PK 8165; PK-8165; PK8165; Pipequaline HCl; Pipequaline hydrochloride |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C22H25ClN2 |
| Exact Mass | 316.1939 |
| Molecular Weight | 352.906 |
| Elemental Analysis | C, 74.88; H, 7.14; Cl, 10.05; N, 7.94 |
| IUPAC/Chemical Name | 2-Phenyl-4-(2-(4-piperidinyl)ethyl)quinoline monohydrochloride |
| InChi Key | JWEMPGHGMSUJIS-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C22H24N2.ClH/c1-2-6-18(7-3-1)22-16-19(11-10-17-12-14-23-15-13-17)20-8-4-5-9-21(20)24-22;/h1-9,16-17,23H,10-15H2;1H |
| SMILES Code | [H]Cl.C1(C2=CC=CC=C2)=NC3=CC=CC=C3C(CCC4CCNCC4)=C1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |