1-NM-PP1
1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively).
Supplier | BOC Sciences |
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Product # | 221244-14-0 |
Pricing | Inquire |
Cas | 221244-14-0 |
Molecular Weight | 331.41424 |
Molecular Formula | C20H21N5 |
Canonical SMILES | CC(C)(C)N1C2=C(C(=N1)CC3=CC=CC4=CC=CC=C43)C(=NC=N2)N |