DMTr-2'-O-TBDMS-5-OMe-rU-3'-CE-Phosphoramidite

DMTr-2'-O-TBDMS-5-OMe-rU-3'-CE-Phosphoramidite is employed in oligonucleotide synthesis and features a TBDMS (tert-butyldimethylsilyl) group at the 2'-O position, and a methoxy (OMe) group on the uracil (rU) nucleoside. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is used to introduce modified uracil residues with increased stability and altered base pairing properties into nucleic acid sequences, suitable for various research applications including RNA structural studies, aptamer development, and gene regulation research.

• Supplier: BOC Sciences
• Product #: BRP-00560
• Molecular Weight: 891.09
• Molecular Formula: C46H63N4O10PSi
• Canonical SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=C(C(=O)NC2=O)OC)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC