Talabostat
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13233 |
| CAS # | 149682-77-9 |
| Pricing | inquire |
| Biological Activity | Talabostat (Val-boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8/9 (IC50 = 4/11 nM; Ki = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities[1][2][3]. |
| Synonyms | Val-boroPro; PT100 |
| MWt | 214.07 |
| Formula | C₉H₁₉BN₂O₃ |
Citations for this product:
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bioRxiv - Neuroscience 2024Quote: ... brain slices were placed in ACSF supplemented with carbogen-containing inhibitors (Val-BoroPro, MedChemExpress, HY-13233A; Sitagliptin, MedChemExpress, HY-13749B) 30 min before placement in the chamber ...