Taccalonolide A

Supplier MedChemExpress
Product # HY-N2416-10 mg
CAS # 108885-68-3
Pricing 10 mg, USD $686.0
Biological Activity Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri, with cytotoxic and antimalarial activities[1][2]. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis[1]. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells[3].
MWt 702.74
Formula C₃₆H₄₆O₁₄
Feedback