Native Bovine Hemoglobin Glutamer

Hemoglobin Glutamer is a cell-free polymerized hemoglobin solution that not only carries oxygen in the plasma, but also enhances the ability of native red blood cells to take up and off-load oxygen. Studies in an artificial capillary model suggest that the free hemoglobin molecules in the plasma facilitate the diffusion of oxygen into the pulmonary capillary blood more rapidly and more efficiently than normal diffusion across the alveolarcapillary barrier and the red blood cell membrane. Hemoglobin Glutamer is manufactured from a plentiful and well-controlled source material, bovine hemoglobin. Only cattle from the qualified farms are utilized as donors, and an extensive herd-management programme ensures that only certified disease-free animals less than 30 months of age are used to provide the hemoglobin. The extensive extraction and purification process used in production has been validated for the removal of potential contaminants including plasma proteins, red blood cell stroma, endotoxin, bacteria, viruses and the agents that are thought to cause transmissible spongiform encephalopathies such as bovine spongiform encephalopathy (BSE) and variant Creutzfeldt Jakob disease (vCJD). This process produces a sterile, pyrogen-free balanced salt solution containing glutaraldehyde cross-linked bovine hemoglobin polymers, which range in size from 65 to 500 kDa.

• Supplier: Creative Biomart
• Product #: Hemoglobin Glutamer-01B