Immortalized Human Brain Microvascular Endothelial Cells - SV40
Immortalized Human Brain Microvascular Endothelial Cells- SV40 from Ace Therapeutics are a specialized cell line developed by immortalizing primary cells using SV40 Large T antigen. These cells have been extensively characterized and demonstrated to maintain the immune barrier properties of primary HBMECs. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | BBM-C-151 |
| Pricing | Inquiry |
| Product Category | Immortalized Cells |
| Species | Human |
| Applications | Immortalized Human Brain Microvascular Endothelial Cells (IM-HBMECs) offer a cost-effective and practical solution for constructing in vitro models of the blood-brain barrier (BBB). These immortalized cells exhibit exceptional fidelity in terms of barrier resistance, immune migration profiles, and responsiveness to inflammatory cytokines. With their specialized BBB endothelial phenotype, this newly established human cell line provides a readily available in vitro model for studying the properties of the human BBB. IM-HBMECs are particularly valuable for investigating central nervous system infections, offering a valuable alternative to primary brain endothelial cells as a reliable model for studying the blood-brain barrier in such studies. |
| Citation Guidance | If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. |
| Source | Brain |
| Recommended Medium | It is recommended to useImmortalized Human Brain Microvascular Endothelial Cells MMedium Kit for culturing in vitro.for culturing in vitro. |
| Cell Type | Endothelial |
| Disease | Normal |
| Quality Control | Real Time PCR was used to quantify SV40 gene expression in immortalized cell line. |
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