TRV-120027 acetate
TRV-120027 acetate, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV-120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV-120027 has the potential for acute decompensated heart failure (ADHF) treatment.
| Supplier | BOC Sciences |
|---|---|
| Product # | BAT-016424 |
| Pricing | Inquire |
| Molecular Weight | 986.14 |
| Molecular Formula | C45H71N13O12 |
| Canonical SMILES | CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(C)C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC.CC(=O)O |