Human Proteasome Subunit Beta Type 3 (PSMB3) Protein

Proteasome Subunit Beta Type 3 (PSMB3) is a recombinant enzyme. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12.

• Supplier: Abbexa Ltd.
• Product #: abx073543-1MG
• Host: E. coli
• Tested Applications: SDS-PAGE
• UniProt Primary AC: P49720
• Activity: Not tested
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note:
  • This product is for research use only.
  • Not for human consumption, cosmetic, therapeutic or diagnostic use.