| Supplier |
Ace Therapeutics |
| Product # |
NSC2534 |
| Pricing |
Inquiry
|
| Product Size |
100 µg
|
| Purity |
> 95 % as determined by SDS-PAGE
|
| Product Type |
Proteins
|
| Synonyms |
Noggin Protein, Human; SYM1 Protein, Human; SYNS1 Protein, Human
|
| Endotoxin |
< 1.0 EU per μg of the protein as determined by the LAL method
|
| Activity |
Measured by its ability to inhibit recombinant human BMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 0.05-0.3 μg/mL in the presence of 25 ng/mL of recombinant human BMP4.
|
| Protein Construction |
A DNA sequence encoding the human Noggin precursor (NP_005441.1) (Met 1-Cys 232) was fused with a polyhistidine tag at the C-terminus.
|
| Accession# |
NP_005441.1
|
| Expressed Host |
HEK293 Cells
|
| Species |
Human
|
| Predicted N Terminal |
Gln 28
|
| Molecule Mass |
The recombinant human Noggin comprises 216 amino acids after removal of the signal peptide and has a predicted molecular mass of 24.6 kDa. As a result of glycosylation, rhNoggin migrates as an approximately 30 kDa bnd in SDS-PAGE under reducing conditions.
|
| Formulation |
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
|
| Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
|
| Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Reconstitution |
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
|