Thrombospondin-derived Peptide; Cyclic CSVTCG

• Supplier: Creative Peptides
• Product #: X21211
• MolecularWeight: 566.7
• Sequence:
  • One Letter Code: CSVTCG (S-S Bonded)
  • Three Letter Code: H-Cys-Ser-Val-Thr-Cys-Gly-OH(S-S Bonded)
• Storage: -20°C
• Explanation: This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis.
• Reference:
  • 1. Wakiyama, T. et al. Histol Histopathol 16, 345 (2001);
  • 2. Tsuzynski, G. et al. J Cell Biol 120, 513 (1993);
  • 3. Asch, A. et al. Biochem Biophys Res Commun 182, 1208 (1992).