Alectinib Hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13011A-5 mg |
| CAS # | 1256589-74-8 |
| Pricing | 5 mg, USD $72.0 |
| Synonyms | CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride |
| MWt | 519.08 |
| Formula | C₃₀H₃₅ClN₄O₂ |
| Biological Activity | Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2]. |
| Purity | 99.89% |