IWP-2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13912-50 mg |
| CAS # | 686770-61-6 |
| Pricing | 50 mg, USD $255.0 |
| Biological Activity | IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ[1][2]. |
| Purity | ≥98.0% |
| MWt | 466.6 |
| Formula | C₂₂H₁₈N₄O₂S₃ |