VPS34-IN1

VPS34-IN1 is a potent and selective Vps34 inhibitor with potential anticancer activity. Administration of VPS34-IN1 to cells induces rapid dose-dependent dispersion of specific PtdIns(3)P-binding probes from endosomal membranes within 1 min without affecting the ability of class I PI3K to regulate Akt. Combining class I (GDC-0941) and class III (VPS34-IN1) PI3K inhibitors may serve as a strategy to better analyze the role and regulation of the elusive class II PI3K.
Supplier Alfa Cytology
Product # BC0214
Pricing 5.0 mg, 10.0 mg, 25.0 mg, 50.0 mg, 100.0 mg, 200.0 mg, 500.0 mg, 1.0 g, inquire
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