2'-O-4'-C-Locked-m7GMP sodium salt

2'-O-4'-C-Locked-m7GMP sodium salt is a modified form of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present. Additionally, it contains a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the compound's stability and hybridization affinity, making it useful for various biochemical applications, particularly in RNA research. The addition of a sodium salt enhances the compound's solubility and stability in aqueous solutions. This modified nucleotide is commonly used in enzymatic reactions, RNA capping studies, and investigations of mRNA processing and translation mechanisms due to its resemblance to the structure of eukaryotic mRNA caps.

• Supplier: BOC Sciences
• Product #: BRP-00669
• Molecular Weight: 389.26 (free acid)
• Molecular Formula: C12H16N5O8P (free acid)