Ilorasertib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16018A-100 mg |
| CAS # | 1847485-91-9 |
| Pricing | 100 mg, USD $1100.0 |
| Synonyms | ABT-348 hydrochloride |
| MWt | 525.0 |
| Formula | C₂₅H₂₂ClFN₆O₂S |
| Biological Activity | Ilorasertib (ABT-348 hydrochloride) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively. Ilorasertib (ABT-348 hydrochloride) also suppresses RET tyrosine kinase, PDGFRβ and Flt1 with IC50s of 7 nM, 3 nM and 32 nM, respectively[1]. |
| Purity | 98.91% |