Duocarmycin A
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12455 |
| CAS # | 118292-34-5 |
| Pricing | inquire |
| Biological Activity | Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC-2 cells typically apoptotic changes, including chromatin condensation, sub-G1 accumulation in DNA histogram pattern, and decrease in procaspase-3 and 9 levels[1]. |
| MWt | 507.49 |
| Formula | C₂₆H₂₅N₃O₈ |