ACV 1

• Supplier: Creative Peptides
• Product #: R0866
• CAS #: 740980-24-9
• LabelingTarget: Neuronal nicotinic receptor
• Synonyms: Conotoxin Vc1.1
• MolecularFormula: C71H103N23O25S4
• MolecularWeight: 1806.98
• Sequence: GCCSDPRCNYDHPEIC-NH2(Disulfide bridge between Cys2 and Cys8, Cys3 and Cys16)
• Storage: -20°C
• Explanation: ACV 1 is neuronal nicotinic receptor antagonist that displays selectivity for the α9α10 subtype. It can alleviates neuropathic pain in three rat models of human neuropathic pain and accelerate functional recovery of injured neurons.
• Activity: Antagonist
• InChI: InChI=1S/C71H103N23O25S4/c1-3-32(2)55-68(117)89-44(56(74)105)27-120-122-30-47-65(114)88-43(26-95)62(111)87-42(23-54(103)104)70(119)94-18-6-8-48(94)66(115)81-36(7-4-16-78-71(75)76)57(106)90-46(29-123-121-28-45(63(112)91-47)80-51(98)24-72)64(113)84-39(21-50(73)97)60(109)83-38(19-33-10-12-35(96)13-11-33)59(108)85-40(22-53(101)102)61(110)86-41(20-34-25-77-31-79-34)69(118)93-17-5-9-49(93)67(116)82-37(58(107)92-55)14-15-52(99)100/h10-13,25,31-32,36-49,55,95-96H,3-9,14-24,26-30,72H2,1-2H3,(H2,73,97)(H2,74,105)(H,77,79)(H,80,98)(H,81,115)(H,82,116)(H,83,109)(H,84,113)(H,85,108)(H,86,110)(H,87,111)(H,88,114)(H,89,117)(H,90,106)(H,91,112)(H,92,107)(H,99,100)(H,101,102)(H,103,104)(H4,75,76,78)
• InChIKey: KJQOYUHYAZGPIZ-UHFFFAOYSA-N
• Purity: >99 %
• LongTermStorageConditions: -20°C