Ezatiostat hydrochloride

Supplier MedChemExpress
Product # HY-13634
CAS # 286942-97-0
Pricing inquire
Biological Activity Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment[1][2].
Synonyms TER199; TLK199 hydrochloride
MWt 566.11
Formula C₂₇H₃₆ClN₃O₆S
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