Ezatiostat hydrochloride
Supplier | MedChemExpress |
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Product # | HY-13634 |
CAS # | 286942-97-0 |
Pricing | inquire |
Biological Activity | Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment[1][2]. |
Synonyms | TER199; TLK199 hydrochloride |
MWt | 566.11 |
Formula | C₂₇H₃₆ClN₃O₆S |