Human Anti-TNFRSF10B Recombinant Antibody (clone TR2-3); scFv Fragment
Provided is a antibody capable of specific binding and capable of activating human death receptor 5 (DR5), and belongs to a full-humanized antibody. The antibody is obtained by performing quintuple screening in a high-capacity full-humanized phage antibody library by using human death receptor DR5 extracellular protein as a target antigen. Pharmacodynamic experiments prove that the antibody is efficient in suppressing the growth of DR5 positive colon cancer cell COLO205 and breast cancer cell MDA-MB-231. The antibody has the advantages such as low immunogenicity, high specificity and high penetrability and is an ideal targeting tumor therapeutic drug.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-M0231-YC-S(P) |
| Pricing | Inquiry |
| Host | Human |
| Target | TNFRSF10B |
| Species Reactivity | Human |
| Type | Human scFv |
| Applications | ELISA, WB |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |