CKI-7

Supplier MedChemExpress
Product # HY-W011109
CAS # 1177141-67-1
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Biological Activity CKI-7 is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 is a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 has a much weaker effect on casein kinase II and other protein kinases[1][2][3][4].
MWt 358.67
Formula C₁₁H₁₄Cl₃N₃O₂S
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