Anti-BetaGamma (MPS-Phosducin-like protein C terminus)
It is a membrane-permeable phosphoducin-like anti-βγ peptide, whose membrane-permeable sequence (MPS) is derived from the C-terminal residues of phosducin-like protein (PhLP). This region of PhLP has been shown to confer interactions with Gβϒ-mediated signaling. Specifically, it inhibits the activity of Go GTPase, demonstrates the ability to bind Gβγ, and inhibits the Gβγ-enhanced rhodopsin phosphorylation via βARK. The PhLP shares amino acid sequence homology with phosphoducin, a phosphoprotein expressed in the retina and pineal gland.
Supplier | BOC Sciences |
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Product # | BAT-013323 |
Pricing | Inquire |
Molecular Weight | 4601.36 |
Molecular Formula | C217H340N46O63 |