| Supplier |
Creative Peptides |
| Product # |
A55004 |
| Pricing |
Inquire
|
| MolecularWeight |
1881.4
|
| Sequence |
- One Letter Code: 5-FAM-klaklakklaklak-NH2
- Three Letter Code: 5-FAM-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-NH2
|
| Storage |
-20°C
|
| Explanation |
This is the pro-apoptotic peptide composed of D-amino acids, 5-FAM labeled. This alpha-helical amphipathic peptide is toxic to eukaryotic cells if internalized by a suitable targeting mechanism. It disrupts mitochondrial membranes upon receptor-mediated cell internalization and causes programmed cell death.
|
| Reference |
- 1. Marks, A. et al. Cancer Res. 65, 2373 (2005);
- 2. Kolonin, M. et al. Nat. Med. 10, 625 (2004).
|