VU 6010572
VU 6010572 is a negative allosteric modulator (NAM) for mGlu. VU 6010572 has an IC50 of 245 nM for mGlu3 with high selectivity among all mGlu receptors. VU 6010572 is highly CNS penetrant.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1261 |
| CAS # | 2126784-39-0 |
| Pricing | Customizable size, Inquiry |
| Synonym | VU 6010572; VU-6010572; VU6010572 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C20H18FNO3 |
| Exact Mass | 339.1271 |
| Molecular Weight | 339.37 |
| Elemental Analysis | C, 70.78; H, 5.35; F, 5.60; N, 4.13; O, 14.14 |
| IUPAC/Chemical Name | (S)-1-(4-fluorophenyl)-4-(2-phenoxypropoxy)pyridin-2(1H)-one |
| InChi Key | AUMJXOXUSGIUCB-HNNXBMFYSA-N |
| InChi Code | InChI=1S/C20H18FNO3/c1-15(25-18-5-3-2-4-6-18)14-24-19-11-12-22(20(23)13-19)17-9-7-16(21)8-10-17/h2-13,15H,14H2,1H3/t15-/m0/s1 |
| SMILES Code | FC(C=C1)=CC=C1N2C=CC(OC[C@H](C)OC3=CC=CC=C3)=CC2=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |