Acetylthiomethyl-diphenylphosphine borane complex

Supplier Alfa Chemistry
Product # ACM446822715-1
CAS # 446822-71-5
Pricing Inquire
Synonyms AGN-PC-005LSK, boron;S-(diphenylphosphanylmethyl) ethanethioate, Acetylthiomethyl-diphenylphosphine borane complex, 446822-71-5
IUPAC Name boron;S-(diphenylphosphanylmethyl) ethanethioate
Purity 96%
MolecularFormula C₁₅H₁₈BOPS
MolecularWeight 288.15
Application Traceless Staudinger ligation reagent with borane protecting group. The borane group stabilizes the phosphine against oxidation and can be easily removed with mild basic or acidic conditions to yield the active phosphine. After reaction with an azide, the phosphine is eliminated in the presence of water to yield a native amide bond. Used in the synthesis of cyclic peptides.
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