Raphin 1
Raphin 1 is an orally bioavailable and BBB-penetrant inhibitor of the regulatory subunit PPP1R15B of protein phosphatase, displays >30-fold selectivity for PPP1R15B over PPP1R15A. Raphin 1 inhibits PPP1R15B-mediated dephosphorylation and protein synthesis in vitro. It was shown to be effective in a mouse model of Huntington's disease.
| Supplier | BOC Sciences |
|---|---|
| Product # | 2022961-17-5 |
| Pricing | Inquire |
| Cas | 2022961-17-5 |
| Molecular Weight | 231.08 |
| Molecular Formula | C8H8Cl2N4 |
| Canonical SMILES | C1=CC(=C(C(=C1)Cl)Cl)C=NN=C(N)N |