Penitrem A

Supplier MedChemExpress
Product # HY-N6776
CAS # 12627-35-9
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Biological Activity Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals[1][2].
MWt 634.2
Formula C₃₇H₄₄ClNO₆
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