PF-04859989 HCl
PF-04859989 HCl is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid. PF-04859989 HCl has been implicated in several psychiatric and neurological disorders, including schizophrenia and bipolar disorder.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD575 |
| CAS # | 177943-33-8 (PF-04859989 HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | PF-04859989 HCl; PF-04859989HCl; PF-04859989; PF 04859989; PF04859989. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C7H6BrCl2NO2 |
| Molecular Weight | 286.934 |
| Elemental Analysis | C, 29.30; H, 2.11; Br, 27.85; Cl, 24.71; N, 4.88; O, 11.15 |
| IUPAC/Chemical Name | 2-(Bromomethyl)-1-chloro-3-nitrobenzene HCl |
| InChi Key | MVBWOEUQKOAQOW-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C7H5BrClNO2.ClH/c8-4-5-6(9)2-1-3-7(5)10(11)12;/h1-3H,4H2;1H |
| SMILES Code | O=[N+](C1=C(CBr)C(Cl)=CC=C1)[O-].[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Schizophrenia |
| Availability | 2 Weeks |