A 419259 trihydrochloride
Potent Hck inhibitor (IC50 = 0.43 nM). Also inhibits other Src family kinases (SFKs). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Also inhibits acute myeloid leukemia (AML) stem cell proliferation in vitro and in vivo.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1435934-25-0 |
| Pricing | Inquire |
| Cas | 1435934-25-0 |
| Molecular Weight | 592.0 |
| Molecular Formula | C29H37Cl3N6O |
| Canonical SMILES | CN1CCN(CC1)C2CCC(CC2)N3C=C(C4=C3N=CN=C4N)C5=CC=C(C=C5)OC6=CC=CC=C6.Cl.Cl.Cl |