XD 14
XD 14 is a BET bromodomain inhibitor (Kd = 160, 170, 380, 490, 830 and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2) respectively). XD 14 also inhibits BRDT(1), CBP, p300 and BRDT(2) (Kd = 1.2, 1.6, 2.6 and 3.7 μM, respectively). XD 14 inhibits proliferation of HL-60 leukemia cells in vitro.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1370888-71-3 |
| Pricing | Inquire |
| Cas | 1370888-71-3 |
| Molecular Weight | 421.51 |
| Molecular Formula | C20H27N3O5S |
| Canonical SMILES | CCC1=C(NC(=C1C(=O)C)C)C(=O)NC2=C(C=CC(=C2)S(=O)(=O)N(CC)CC)O |