UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase

Involved with EC 6.3.2.4 (D-alanine-D-alanine ligase), EC 6.3.2.7 (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase) or EC 6.3.2.13 (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase), EC 6.3.2.8 (UDP-N-acetylmuramate-L-alanine ligase) and EC 6.3.2.9 (UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase) in the synthesis of a cell-wall peptide (click here) for diagram. This enzyme also catalyses the reaction when the C-terminal residue of the tripeptide is meso-2,4-diaminoheptanedioate (acylated at its L-centre), linking the D-Ala-D-Ala to the carboxy group of the L-centre. This activity was previously attributed to EC 6.3.2.15, which has since been deleted.

• Supplier: Creative Enzymes
• Product #: EXWM-5731
• CAS: 55354-36-4