12,14-Dichlorodehydroabietic acid
Supplier | MedChemExpress |
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Product # | HY-133596 |
CAS # | 65281-77-8 |
Pricing | inquire |
Biological Activity | 12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, is a potent Ca2+-activated K+ (BK) channel opener. 12,14-Dichlorodehydroabietic acid blocks GABA-dependent chloride entry in mammalian brain and operates as a non-competitive GABAA antagonist. 12,14-Dichlorodehydroabietic acid increases cytosolic free Ca2+ and stimulates transmitter release[1][2]. |
MWt | 369.33 |
Formula | C₂₀H₂₆Cl₂O₂ |