12,14-Dichlorodehydroabietic acid

Supplier MedChemExpress
Product # HY-133596
CAS # 65281-77-8
Pricing inquire
Biological Activity 12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, is a potent Ca2+-activated K+ (BK) channel opener. 12,14-Dichlorodehydroabietic acid blocks GABA-dependent chloride entry in mammalian brain and operates as a non-competitive GABAA antagonist. 12,14-Dichlorodehydroabietic acid increases cytosolic free Ca2+ and stimulates transmitter release[1][2].
MWt 369.33
Formula C₂₀H₂₆Cl₂O₂
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