3,4',5-Trimethoxystilbene
3,4',5-Trimethoxystilbene is isolated from the herbs of Virola cuspidata. 3,4',5-Trimethoxystilbene exerts antiallergic and anti-mitotic properties. It shows antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation. 3,4',5-Trimethoxystilbene is a potent small molecule inducer of autophagy in human umbilical vascular endothelial cells (HUVECs) in the presence of serum. It has anti-inflammatory activity, the ability of it to induce HO-1 expression may provide one of possible mechanisms of its anti-inflammatory action. 3,4',5-Trimethoxystilbene shows potent antitumor and anti-HCV activities without exhibiting cytotoxicity to human hepatocytes in vitro or in mice livers. It acts as an inhibitor of tubulin polymerization.
Supplier | BOC Sciences |
---|---|
Product # | 22255-22-7 |
Pricing | Inquire |
Cas | 22255-22-7 |
Molecular Weight | 270.32 |
Molecular Formula | C17H18O3 |
Canonical SMILES | COC1=CC=C(C=C1)C=CC2=CC(=CC(=C2)OC)OC |