Apolipoprotein B (ApoB) Antibody

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypo beta lipoproteinemia, normotriglyceridemic hypo beta lipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

• Supplier: Abbexa Ltd.
• Product #: abx012218-100UL
• Clonality: Monoclonal
• Conjugation: Unconjugated
• Host: Mouse
• Tested Applications: ELISA, IF/ICC, FCM
• UniProt Primary AC: P04114
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note: This product is for research use only.