Desvenlafaxine
Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause. Desvenlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. (Source: https://en.wikipedia.org/wiki/Desvenlafaxine).
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD775 |
| CAS # | 93413-62-8 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | Pristiq; Desfax |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C16H25NO2 |
| Exact Mass | 263.18853 |
| Molecular Weight | 263.38 |
| Elemental Analysis | C, 72.96; H, 9.57; N, 5.32; O, 12.15 |
| IUPAC/Chemical Name | 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol |
| InChi Key | KYYIDSXMWOZKMP-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3 |
| SMILES Code | CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |