| Supplier |
Creative Peptides |
| Product # |
X21198 |
| Pricing |
Inquire
|
| MolecularWeight |
1418.5
|
| Sequence |
- One Letter Code: RPVSSAApSVYAGAC
- Three Letter Code: H-Arg-Pro-Val-Ser-Ser-Ala-Ala-pSer-Val-Tyr-Ala-Gly-Ala-Cys-OH
|
| Storage |
-20°C
|
| Explanation |
This peptide corresponds to human keratin K18 amino acids 26-38, with an additional C-terminal cysteine. The sequence is identical to mouse K18 except that human K18 Val28 is replaced by alanine in the mouse sequence. Members of the 14-3-3 protein family bind the human intermediate filament protein keratin 18 (K18) in-vivo, in a cell-cycle- and phosphorylation-dependent manner. K18 Ser33 phosphorylation is essential for the association of K18 with 14-3-3 proteins and plays a role in keratin organization and distribution.
|
| Reference |
Ku, NO. et al. EMBO J. 17, 1892 (1998).
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