POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody
This gene encodes a transcription factor containing a POU homeodomain.This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency.A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21;q12), has been linked to tumor formation.Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon.Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain.Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.Low levels of expression in adult tissues.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx016067-100UL |
| Pricing | 100 µl USD $420.5 |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Host | Mouse |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| UniProt Primary AC | Q01860 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |