EGFR-IN-1 TFA

Supplier MedChemExpress
Product # HY-19617B-5 mg
Pricing 5 mg, USD $480.0
Biological Activity EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 TFA potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 TFA displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity[1].
Purity 99.05%
MWt 628.6
Formula C₃₀H₃₁F₃N₆O₆
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