c[G(2',5')pS-A(3',5')pS], isomer 1 and isomer 2
c[G(2',5')pS-A(3',5')pS] is an isomeric di-thiophosphate analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is resistant against the 2'3'-cGAMP hydrolysing enzyme ENPP1, and compared to natural 2'3'-cGAMP, it exhibits higher potency in inducing IFN-β secretion from human THP1 monocytes.
Supplier | BOC Sciences |
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Product # | 1638242-56-4 / 1638243-00-1 |
Pricing | Inquire |
Cas | 1638242-56-4 / 1638243-00-1 |
Molecular Weight | 706.6 (free acid) |
Molecular Formula | C20H24N10O11P2S2 (free acid) |